Chronic Idiopathic Thrombocytopenic Purpura

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Anticoagulant therapy in chronic idiopathic thrombocytopenic purpura.

By RIai iiD J. COHEN, LEWIS H. DENNIS AND MARCEL E. CONRAD T HE PARENTERAL ADMINISTRATION of small doses of heparin to normal adults1 and to patients with arteriosclerotic heart disease2 has no measurable effect on blood platelet economy. However, larger amounts of heparin1 and therapeutic doses of bishydroxycoumarin ( Dicumarol) distinctly prolong tile survival of circulating platelets.3’4 The...

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Chronic idiopathic thrombocytopenic purpura: primum non nocere.

The vast majority of children with idiopathic thrombocytopenic purpura, dramatic though their signs may be at presentation, remit within weeks, with or perhaps despite medical attention. Such children, when referred to the Queen Elizabeth Hospital, Hackney Road by their family doctor, or appearing in the busy casualty department, have a careful history taken with particular emphasis given to th...

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Platelet aggregation in chronic idiopathic thrombocytopenic purpura.

A method for washing platelets by albumin density gradient separation has been modified to prepare platelet rich plasma of thrombocytopenic patients for platelet aggregation studies. The concentration procedure, consisting of centrifuging platelets into a specific gravity gradient between plasma and 40-45% aqueous solution of bovine albumin, does not affect platelet aggregation adversely. Plate...

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Chronic idiopathic thrombocytopenic purpura: mechanisms of pathogenesis.

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Unusual presentation of chronic idiopathic thrombocytopenic purpura.

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ژورنال

عنوان ژورنال: Archives of Internal Medicine

سال: 1973

ISSN: 0003-9926

DOI: 10.1001/archinte.1973.03650090062011